Although people with psoriatic arthritis (PsA) can develop lymphoma, there is currently no evidence that PsA increases the risk of lymphoma. Further research is necessary to understand the link between these conditions.

Lymphoma is a type of cancer that originates in the lymphatic system. The two main types of lymphoma are Hodgkin’s lymphoma and non-Hodgkin’s lymphoma.

PsA is a chronic inflammatory condition that affects the joints, often occurring in individuals with psoriasis.

This article delves into the relationship between these conditions, exploring whether PsA increases the risk of developing lymphoma and whether it can cause lymphoma. It also discusses available treatments and more.

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A 2020 review suggests people with psoriasis may have a higher risk of developing cancer, especially lymphomas. However, the review’s authors state that more research is necessary to determine a link between PsA and lymphomas.

A 2018 article supports these findings, suggesting those with psoriasis may be more prone to developing lymphomas, particularly cutaneous T-cell lymphoma.

However, this research does not suggest that having PsA puts a person at a higher risk of developing cancer.

Psoriasis is an autoimmune condition that causes inflammation and scaly lesions on the skin. Some people with PsA may also have psoriasis, which may increase their risk of developing lymphomas.

While a person with PsA can develop lymphoma, more research is necessary to determine whether there is a causal link between the two conditions.

Can psoriatic arthritis cause lymphoma?

Currently, there is no evidence that PsA is a direct cause of lymphoma. However, some research suggests that chronic inflammation due to psoriasis may contribute to the development of comorbidities, including lymphoma.

Like psoriasis, PsA is a chronic, inflammatory condition. A 2019 article suggests chronic inflammation can lead to cell mutation and increase the likelihood of cancerous cell growth, potentially triggering lymphoma.

However, it is important to note that current research has not found that people with PsA are at higher risk for developing lymphomas.

Treatment options for PsA and lymphoma are different. A person’s treatment plan may also depend on the severity of their PsA and the stage of cancer.

Treating PsA

There is currently no cure for PsA, and treatment focuses on managing symptoms and preventing joint damage. Doctors may prescribe the following treatment options for people with this condition:

  • Corticosteroid injections: Doctors can inject corticosteroids into the joints to deal with inflammation.
  • Disease-modifying anti-rheumatic drugs (DMARDs): DMARDs, such as methotrexate, can help reduce the immune system response and lessen symptoms of PsA.
  • Biologics: Biologics target the immune system’s messaging system and decrease inflammation.

Doctors may also recommend lifestyle changes, such as maintaining a moderate weight, exercising regularly, and getting plenty of rest.

Treating lymphoma

Lymphoma treatment may depend on the type and stage of the cancer. According to the National Cancer Institute (NCI), common approaches include:

A team of oncologists can determine and tailor a treatment plan to a person’s needs.

PsA is a lifelong condition without a current cure. However, with proper management and timely medical care, most individuals with PsA can slow the condition’s progression, decrease pain, and protect their joints.

Lymphoma, being a type of cancer, can be more challenging. A person’s prognosis may depend on the type of lymphoma a person has and the stage of the cancer.

Early detection and prompt treatment are crucial for improving someone’s outcomes.

Early detection is important for both PsA and lymphoma. According to the American Academy of Dermatology Association (AAD), early signs of PsA may include swollen and stiff joints.

The AAD suggests that symptom onset typically occurs 5–12 years after a person develops psoriasis. However, people may develop both conditions simultaneously, and in rare cases, someone might develop PsA first.

Early diagnosis and treatment can relieve PsA symptoms and reduce its effects on a person’s life.

Lymphoma symptoms can vary depending on the type and stage of the cancer. Common signs may include:

If a person experiences persistent or concerning symptoms, they can speak with a doctor to identify the underlying cause.

More research is necessary to determine whether a link between PsA and lymphoma exists. However, having psoriasis, which is common with PsA, may increase the risk of several conditions, including lymphoma.

Both PsA and lymphoma benefit from early diagnosis and treatment. PsA is a lifelong condition, but treatment can help people with lymphoma reach remission.

If a person suspects they have PsA or are experiencing symptoms of lymphoma, it is essential to speak with a doctor promptly.