Wegovy is a brand-name subcutaneous injection that’s prescribed for weight management. Wegovy contains the active ingredient semaglutide and belongs to the GLP-1 drug class.

The Food and Drug Administration (FDA) has approved Wegovy for long-term weight loss or weight management along with exercise and a low calorie diet. It’s approved for use in adults with either:

Wegovy is also used for long-term weight management in children ages 12 years and older who have a BMI in the 95th percentile or higher (obesity).

Drug details

You’ll find key information about Wegovy below.

The active ingredient in Wegovy is semaglutide. Wegovy is available only as a brand-name medication. It’s not currently available in generic form.

A generic drug is an exact copy of the active drug in a brand-name medication. Generics usually cost less than brand-name drugs.

As with all medications, the cost of Wegovy can vary. The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use. You can refer to this article for details about the cost of Wegovy treatment.

Keep in mind that you may be able to get a 90-day supply of Wegovy. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or your insurance company.

Before approving coverage for Wegovy, your insurance company may require you to get prior authorization. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The insurance company will review the prior authorization request and decide if the drug will be covered.

If you’re not sure if you’ll need to get prior authorization for Wegovy, contact your insurance company.

Cost with insurance

The price you’ll pay for Wegovy with insurance is generally less than you’ll pay without insurance. But your actual cost of Wegovy will vary.

Among other factors, the price depends on your location and the number of injection pens you buy. To find out the exact cost of Wegovy with insurance, talk with your pharmacist or insurance company.

Financial and insurance assistance

If you need financial support to pay for Wegovy, or if you need help understanding your insurance coverage, help is available.

By calling 833-4-WEGOVY (833-493-4689), you can speak with someone who can help explain the cost of Wegovy. They can also help you determine if you’re eligible for savings. For more information about saving money on Wegovy, see right below.

Wegovy coupon or savings card

Novo Nordisk Inc., the manufacturer of Wegovy, offers a savings card to help lower the cost of its drug. This savings card is similar to a coupon.

For more information and to find out if you’re eligible for support, call 833-4-WEGOVY (833-493-4689) or visit the drug’s website. You can also check out this article to learn how to save money on prescriptions.

You can also visit Optum Perks for price estimates of Wegovy. These estimates are based on the use of Optum Perks coupons. Note: Optum Perks coupons cannot be used with any insurance copays or benefits.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

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Mail-order pharmacies

Wegovy may be available through a mail-order pharmacy. Using this service may help lower the drug’s cost and allow you to get your medication without leaving home.

If recommended by your doctor, you may be able to receive a 90-day supply of Wegovy, so there’s less concern about running out of the medication. If you’re interested in this option, check with your doctor, pharmacist, or insurance company. Some Medicare plans may help cover the cost of mail-order medications.

If you don’t have insurance, you can ask your doctor or pharmacist about online pharmacy options.

Generic version

The active ingredient in Wegovy is semaglutide. Wegovy is not available in a generic form. A generic drug is an exact copy of the active drug in a brand-name medication. Generics tend to cost less than brand-name drugs.

The Food and Drug Administration (FDA) approves prescription drugs such as Wegovy to treat certain conditions.

Wegovy is FDA-approved for long-term weight management when used along with exercise and a low calorie diet.

Specifically, Wegovy is used for long-term weight management in adults with either:

Wegovy is also approved for use in children. See “Wegovy and children” just below.

You can learn more about obesity and weight management by visiting Medical News Today’s weight management hub.

Limitations of use

It’s important to note that you should not use Wegovy with other glucagon-like peptide-1 (GLP-1) agonists. (GLP-1 agonists is a group of drugs that Wegovy belongs to.)

It is unknown if Wegovy is safe or effective when used with other weight management drugs.

It is unknown if Wegovy is safe for people with a history of pancreatitis (inflammation of the pancreas). The drug’s use in people with pancreatitis has not been studied.

Effectiveness for weight loss and weight management

Wegovy has been found to be effective for long-term weight loss and weight management in clinical studies.

For more information on how Wegovy performed in clinical studies, see the drug’s prescribing information.

Wegovy and children

Wegovy is approved for long-term weight loss or management in children ages 12 years and older who have a BMI in the 95th percentile or higher.

A percentile refers to a child’s BMI relative to other children of the same age and sex. Being in the 95th percentile means that a child is estimated to have more body fat than 95% of children of the same age and sex. This is considered obesity.

How to buy Wegovy

If you think Wegovy could be a good weight management option for you, talk with your doctor. They can help determine whether Wegovy might be right for you and provide a prescription.

Another easy way to purchase Wegovy is by using a telemedicine provider such as Calibrate or Ro Body. Through these services, a licensed telehealth professional will give you a health evaluation. If the evaluation shows that Wegovy could be a helpful option for you, the telehealth professional may provide an electronic prescription. You can then use this prescription to order the medication through the service’s site. After you start taking the medication, the service will provide coaching and other support to help you manage your weight.

If you get a Wegovy prescription through Calibrate or Ro Body, we encourage you to tell your doctor. It’s important that your doctor knows about all medications you take.

Wegovy is approved for long-term weight management when used along with exercise and a low calorie diet. It is unknown if Wegovy is safe or effective when used with other weight loss or weight management drugs.

Note: You should not use Wegovy with other glucagon-like peptide-1 (GLP-1) agonists. (GLP-1 agonists is the group of drugs that Wegovy belongs to.)

Wegovy can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Wegovy. These lists do not include all possible side effects.

For more information about the possible side effects of Wegovy, talk with your doctor or pharmacist. They can give you tips on how to manage any side effects that may concern or bother you.

Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. If you would like to notify the FDA about a side effect you’ve had with Wegovy, you can do so through MedWatch.

Mild side effects

Mild side effects* of Wegovy can include:

Most of these side effects may go away within a few days to a couple of weeks. But if they become more severe or don’t go away, talk with your doctor or pharmacist.

* This is a partial list of mild side effects from Wegovy. To learn about other mild side effects, talk with your doctor or pharmacist or view Wegovy’s prescribing information.

Serious side effects

Serious side effects from Wegovy aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.

Serious side effects and their symptoms can include:

* For more information about this side effect, see “Side effect details” below.
† Wegovy has a boxed warning for this side effect. A boxed warning is the strongest warning required by the FDA. It alerts doctors and patients about drug effects that may be dangerous.

Suicide prevention

If you know someone at immediate risk of self-harm, suicide, or hurting another person:

  • Ask the tough question: “Are you considering suicide?”
  • Listen to the person without judgment.
  • Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor.
  • Stay with the person until professional help arrives.
  • Try to remove any weapons, medications, or other potentially harmful objects if it’s safe to do so.

If you or someone you know is having thoughts of suicide, a prevention hotline can help. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988.

Find more links and local resources.

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Side effects in children

Generally, the side effects of Wegovy in children are expected to be similar to those in adults. However, gallbladder problems were more common in children than adults in clinical trials.

Gallbladder problems can include gallstones (lumps in the gallbladder) and cholecystitis (inflammation of the gallbladder). You can refer to “Gallbladder problems” under “Side effect details” below for details about this side effect.

Side effect details

Here’s some detail on certain side effects this drug may cause. In addition to the information below, you can also refer to this in-depth article about Wegovy’s side effects.

Risk of thyroid cancer

Wegovy has a boxed warning about the possible risk of thyroid cancer. A boxed warning is the most serious warning from the FDA. It alerts doctors and patients about drug effects that may be dangerous.

Animal studies found an increased risk of thyroid cancer in rats that were given Wegovy. But animal studies don’t always predict what will happen in humans. It is not known for sure if Wegovy increases the risk of thyroid cancer in humans.

If you or a family member has a history of medullary thyroid carcinoma (MTC), your doctor will not prescribe Wegovy for you. MTC is a rare type of thyroid cancer. Your doctor also won’t prescribe Wegovy if you have multiple endocrine neoplasia syndrome type 2 (MEN2). MEN2 is a rare genetic (inherited) condition that can cause thyroid cancer.

Symptoms of thyroid cancer can include:

Tell your doctor right away if you have any symptoms of thyroid cancer. They can advise on the cause of these symptoms and recommend treatment options for your condition.

Pancreatitis

Pancreatitis (inflammation of the pancreas) is a rare but serious side effect of Wegovy.

Symptoms of pancreatitis can include:

  • pain in the center of the abdomen, which may get worse after eating
  • nausea or vomiting
  • diarrhea
  • loss of appetite
  • jaundice (yellowing of the skin or whites of the eyes)

Tell your doctor right away if you have symptoms of pancreatitis while taking Wegovy. They’ll check you for this condition. If you have pancreatitis, they’ll likely prescribe a drug other than Wegovy for you.

Gallbladder problems

Gallbladder problems, such as gallstones (lumps in the gallbladder) and inflammation of the gallbladder, are rare but serious side effects of Wegovy. In clinical trials, this type of side effect was more common in children using Wegovy than in adults.

Symptoms of gallstones or gallbladder inflammation may include:

If you have symptoms of gallbladder problems while taking Wegovy, talk with your doctor. They’ll give you tests to check for this condition. Your doctor can advise if it’s safe for you to keep taking Wegovy.

Allergic reaction

As with most drugs, some people can have an allergic reaction after taking Wegovy. This side effect wasn’t reported in Wegovy’s clinical trials. But allergic reaction has been reported in people taking the drug after it became available on the market.

Symptoms of a mild allergic reaction can include:

A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:

  • angioedema (swelling under your skin, typically in your eyelids, lips, hands, or feet)
  • swelling of your tongue, mouth, or throat
  • trouble breathing

Call your doctor right away if you have an allergic reaction to Wegovy, as the reaction could become severe. Call 911 or your local emergency phone number if your symptoms feel life threatening or if you think you’re having a medical emergency.

Below are answers to some frequently asked questions about Wegovy.

Are there any reviews available from people who have taken Wegovy?

No, the manufacturer of Wegovy has not provided reviews from people who’ve taken the drug.

You can learn more about what to expect with Wegovy by visiting the manufacturer’s website. Or you can read the drug’s prescribing information.

For more information, talk with your doctor or pharmacist.

How does Wegovy compare with Ozempic, Trulicity, and Victoza?

Wegovy, Ozempic, Trulicity, and Victoza all belong to a group of drugs called glucagon-like peptide-1 (GLP-1) agonists. But they have some important differences.

Both Wegovy and Ozempic contain the active drug semaglutide. Trulicity contains the active drug dulaglutide, and Victoza contains the active drug liraglutide.

Ozempic, Trulicity, and Victoza are approved to treat type 2 diabetes and to lower the risk of serious cardiovascular problems in certain people. Wegovy isn’t approved for these uses. Instead, Wegovy is approved for long-term weight management in certain adults and children when used along with exercise and a low calorie diet. (For details, see the “Wegovy for weight loss and weight management” section above.)

For more information about how Wegovy compares with Ozempic, Trulicity, and Victoza, talk with your doctor or pharmacist. You can also refer to these articles about Wegovy vs. Mounjaro and Ozempic vs. Wegovy.

Can I see before and after results from Wegovy treatment?

The manufacturer of Wegovy has not provided before and after results from people who have used the drug.

For more information about what to expect with Wegovy, talk with your doctor.

Is Wegovy used to treat type 1 or type 2 diabetes?

No, Wegovy isn’t used to treat type 1 or type 2 diabetes. Wegovy is approved for long-term weight management in certain adults when used along with exercise and a low calorie diet. (For details, see the “Wegovy for weight loss and weight management” section above.)

But semaglutide (the active drug in Wegovy) is also available as the brand-name drugs Ozempic and Rybelsus. Both Ozempic and Rybelsus are approved to treat type 2 diabetes. No form of semaglutide is currently approved to treat type 1 diabetes.

If you’re interested in taking other forms of semaglutide to treat your diabetes, talk with your doctor.

Can I use Wegovy with other weight loss and weight management medications?

It’s not likely. Currently, it is unknown if Wegovy is safe or effective when used with other weight loss and weight management drugs. Before taking Wegovy with other medications, supplements, herbs, or other weight management products, talk with your doctor.

It’s important to note that you should not use Wegovy with other glucagon-like peptide-1 (GLP-1) agonists. (GLP-1 agonists is the group of drugs that Wegovy belongs to.)

Wegovy is meant to be used along with a plan that includes a low calorie diet and regular exercise. Some people may also benefit from behavioral therapy or guidance from a dietitian. Talk with your doctor about other safe ways to manage your weight along with Wegovy.

Other drugs are available for weight loss and weight management. Some may be a better fit for you than others. If you’re interested in finding an alternative to Wegovy, talk with your doctor. They can tell you about other medications that may work well for you.

Examples of other drugs that may be used for weight loss and weight management include:

  • benzphetamine
  • bupropion and naltrexone (Contrave)
  • liraglutide (Saxenda)
  • orlistat (Alli, Xenical)
  • phendimetrazine (Bontril PDM)
  • phentermine (Adipex-P, Lomaira)
  • phentermine and topiramate (Qsymia)

Typically, your doctor will start you on a low dosage of Wegovy. Then they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug form and strengths

Wegovy comes as a liquid solution inside a prefilled, single-dose injection pen.

Wegovy comes in several strengths:

  • 0.25 milligrams per 0.5 milliliters of liquid solution (0.25 mg/0.5 mL)
  • 0.5 mg/0.5 mL
  • 1 mg/0.5 mL
  • 1.7 mg/0.75 mL
  • 2.4 mg/0.75 mL

Each Wegovy pen delivers only one dose of the drug. You’ll use a new Wegovy pen for each dose.

Dosage for weight loss and weight management

The usual starting dose of Wegovy for weight loss is 0.25 mg. You’ll inject this dose once per week for 4 weeks.

Then, your doctor will likely increase your dosage every 4 weeks as follows:

  • 0.5 mg once per week during weeks 5 through 8
  • 1 mg once per week during weeks 9 through 12
  • 1.7 mg once per week during weeks 13 through 16

At week 17 and onward, you’ll start your maintenance (ongoing) dosage of 1.7 mg or 2.4 mg per week. The maintenance dosage your doctor prescribes will depend on how effective Wegovy treatment is for you and how your body responds to the drug, such as whether you’re having side effects.

You’ll likely continue your maintenance dosage long term, according to your doctor’s instructions.

For more information about Wegovy’s dosage, you can refer to this article.

Children’s dosage

The usual starting dosages of Wegovy in children ages 12 years and older are the same as the dosages used in adults, which are described just above.

The usual maintenance (ongoing) dosage of Wegovy in children is 2.4 mg per week.

What if I miss a dose?

What to do if you miss a dose of Wegovy depends on a few factors:

  • If you miss one dose of Wegovy and your next dose is more than 48 hours away, take your missed dose as soon as you remember.
  • If you miss one dose of Wegovy and your next dose is less than 48 hours away, skip your missed dose. Then take your next dose according to your usual schedule.
  • If you miss two or more doses of Wegovy in a row, talk with your doctor. They may need to adjust your dosage temporarily.

If you aren’t sure whether to take a missed dose of Wegovy or to skip it, talk with your doctor or pharmacist.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or using a timer. You could also download a reminder app on your phone.

Will I need to use this drug long term?

Yes, Wegovy may be used as a long-term treatment. If you and your doctor determine that Wegovy is safe and effective for you, you’ll likely use it long term.

You should use Wegovy according to the instructions your doctor gives you.

Wegovy comes as a liquid inside a prefilled, single-dose injection pen. It’s typically given as a subcutaneous injection (an injection under the skin) into your abdomen, upper arm, or thigh.

Your doctor or another healthcare professional will show you how to give yourself Wegovy injections at home. For more Wegovy instructions, you can visit the drug manufacturer’s website. Or you can read these detailed instructions.

When to inject

You’ll self-inject a dose of Wegovy once a week on the same day each week. For example, you might inject the drug every Monday. You can inject Wegovy at any time of day.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or using a timer. You could also download a reminder app on your phone.

Wegovy and food

You can use Wegovy with or without food.

Wegovy belongs to a group of drugs called glucagon-like peptide-1 (GLP-1) agonists. The drug mimics the activity of GLP-1, a natural hormone in the body.

GLP-1 works in your brain to regulate your appetite. The drug mimics GLP-1, which helps lessen your appetite and food intake. This can lead to weight loss. Wegovy is approved for long-term weight loss and weight management in certain adults.

How long does it take to work?

Wegovy starts working right after you inject your first dose. But it may take several weeks for you to notice a decrease in appetite or weight loss.

There aren’t any known interactions between Wegovy and alcohol.

If you drink alcohol, talk with your doctor about how much is safe for you to drink during Wegovy treatment.

Wegovy can interact with several other medications.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Note: In addition to the information below, you can also refer to this in-depth article about Wegovy’s interactions.

Wegovy and other medications

Below is a list of medications that can interact with Wegovy. This list does not contain all drugs that may interact with Wegovy.

Before taking Wegovy, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

Drugs that can interact with Wegovy include:

  • Insulin. These medications are used to treat diabetes. Taking Wegovy with insulin can raise your risk of hypoglycemia (low blood sugar). Examples of these drugs include:
  • Sulfonylureas. These drugs are used to treat diabetes. Taking Wegovy with sulfonylureas can raise your risk of hypoglycemia. Examples of these medications include:
  • Drugs taken by mouth. These are drugs that you take as tablets, capsules, or liquid solutions. If you take any of these medications with Wegovy, your body may not absorb them well enough.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Wegovy and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Wegovy. But you should still check with your doctor or pharmacist before using any of these products while taking Wegovy.

Wegovy and foods

There aren’t any foods that have been specifically reported to interact with Wegovy. If you have any questions about eating certain foods with Wegovy, talk with your doctor.

It’s recommended to stop Wegovy treatment at least 2 months before trying to become pregnant.

Wegovy hasn’t been studied in people who are pregnant or breastfeeding. But in animal studies, the drug caused fetal harm and congenital anomalies (commonly known as birth defects) when given to pregnant animals. Wegovy also passed into the breast milk of lactating animals, meaning the drug could possibly pass to a child who is breastfed. However, animal studies do not always predict what will happen in humans.

If you become pregnant while you’re using Wegovy, you could participate in the drug’s pregnancy registry. Pregnancy registries gather information about how certain drugs can affect pregnancy. For details, you can talk with your doctor, visit the registry website, and call 877-390-2760.

If you’re able to become pregnant, breastfeeding, or planning on either, talk with your doctor before using this medication.

You can also refer to this article for more information. If you have more questions, talk with your doctor.

This drug comes with several precautions.

FDA warning: Risk of thyroid cancer

This drug has a boxed warning. This is the most serious warning from the Food and Drug Administration (FDA). A boxed warning alerts doctors and patients about drug effects that may be dangerous.

Animal studies found an increased risk of thyroid cancer in rats that were given Wegovy. But it isn’t known for sure if Wegovy increases the risk of thyroid cancer in humans.

For more information about this warning, see the “Wegovy side effects” section above.

Other precautions

Before taking Wegovy, talk with your doctor about your health history. Wegovy may not be right for you if you have certain medical conditions or other factors affecting your health. These include:

  • Depression or other mental health conditions: Wegovy may cause suicidal thoughts or behaviors. You may have a higher risk of this side effect if you have depression or other mental health conditions. If you have these conditions, talk with your doctor before you start taking Wegovy.
  • Diabetic retinopathy: Wegovy may cause severe problems related to diabetic retinopathy. If you have diabetic retinopathy, talk with your doctor before starting Wegovy. They may check your eyes regularly while taking the drug.
  • Kidney problems: Before taking Wegovy, tell your doctor about any kidney problems you have. The drug can cause acute (sudden) kidney failure for some people. Your risk of this side effect may be higher if you already have kidney problems.
  • Pancreatitis: Wegovy may cause pancreatitis (inflammation of the pancreas). It is unknown if Wegovy is safe for people who have a history of this condition. If you have pancreatitis or you’ve had it in the past, be sure to tell your doctor before starting Wegovy.
  • Allergic reaction: If you’ve had an allergic reaction to Wegovy or any of its ingredients, you should not take Wegovy. Ask your doctor what other medications are better options for your condition.
  • Pregnancy. It may not be safe to use Wegovy during pregnancy. The drug manufacturer recommends stopping Wegovy treatment at least 2 months before trying to become pregnant. For more information, see the “Wegovy and pregnancy” section above.
  • Breastfeeding. It is unknown if Wegovy is safe to use while breastfeeding. For more information, see the “Wegovy and breastfeeding” section above.

Note: For more information about the potential negative effects of Wegovy, see the “Wegovy side effects” section above.

Taking more than the recommended dosage of Wegovy can lead to serious side effects. Do not use more Wegovy than your doctor recommends.

Overdose symptoms

Symptoms of an overdose can include:

What to do in case of overdose

If you think you’ve taken too much of this drug, call your doctor. You can also call America’s Poison Centers at 800-222-1222 or use its online tool. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away.

When you get Wegovy from the pharmacy, the pharmacist will add an expiration date to the label on the packaging. This date is typically 1 year from the date they dispensed the medication.

The expiration date indicates how long the medication remains effective. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. If you have unused medication that has gone past the expiration date, ask your pharmacist how to dispose of it properly.

Storage

How long a medication remains good to use can depend on many factors, including how and where you store the medication.

You should store Wegovy pens in the refrigerator at a temperature of 36°F to 46°F (2°C to 8°C) until you use them. Or you can temporarily store unopened Wegovy pens at a room temperature of 46°F to 86°F (8°C to 30°C) for up to 28 days. The pens cannot be refrigerated again after being stored at room temperature. Wegovy pens should never be frozen.

Wegovy pens should be stored in their original packaging to protect them from light.

Disposal

Right after you’ve used a Wegovy pen, dispose of it in an FDA-approved sharps disposal container. This helps prevent others, including children and pets, from taking the drug by accident or harming themselves with the needle. You can buy a sharps container online or ask your doctor, pharmacist, or health insurance company where to get one.

This article provides several useful tips on medication disposal. You can also ask your pharmacist for information about how to dispose of your medication.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.