Izervay (avacincaptad pegol) is a brand-name eye injection that’s prescribed for an advanced form of age-related macular degeneration. Izervay is not known to interact with other drugs.

Izervay is prescribed for geographic atrophy caused by age-related macular degeneration in adults.

An interaction occurs when one substance causes another substance to have a different effect than expected.

To learn more about Izervay’s interactions, keep reading. For additional information about Izervay, including details about its uses, see this article.

Izervay isn’t known to interact with other medications. However, that doesn’t mean interactions aren’t possible. For example, other drugs may be approved in the future that may have interactions with Izervay.

Before you start treatment with Izervay, tell your doctor and pharmacist which prescription, over-the-counter, and other medications you take. By sharing this information with them, you may help prevent possible interactions. (To learn whether Izervay interacts with supplements, herbs, or vitamins, see the “Izervay and other interactions” section below.)

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

In some cases, factors or conditions could prevent your doctor from prescribing Izervay due to the risk of harm. These are known as contraindications. The contraindications of Izervay include:

Having an eye infection

If you have an infection in or around your eye, your doctor typically won’t administer Izervay. If you have an eye infection, your doctor will likely prescribe medication to manage the infection before administering Izervay.

Having inflammation inside your eye

Your doctor typically won’t administer Izervay if you have inflammation (swelling) inside your eye. If you have inflammation in your eye, your doctor will likely prescribe medication to lower the inflammation before administering Izervay.

There are no known interactions between Izervay and alcohol.

If you have questions about drinking alcohol during Izervay treatment, talk with your doctor or pharmacist.

Izervay may have other interactions, such as with supplements, foods, vaccines, or even lab tests. You’ll find details below. Keep in mind that the following information does not include all other possible interactions with Izervay.

Izervay and supplements

It’s possible for drugs to interact with supplements such as vitamins and herbs.

Izervay and herbs

There are no specific reports of herbs interacting with Izervay. However, that doesn’t mean herbal interactions won’t occur or be recognized in the future. Because of this, it’s important to check with your doctor or pharmacist before taking any of these products during Izervay treatment.

Izervay and vitamins

There are no specific reports of vitamins interacting with Izervay. However, that doesn’t mean vitamin interactions won’t occur or be recognized in the future. Because of this, you should talk with your doctor or pharmacist before taking any vitamin product with Izervay.

Izervay and food

There were no reports of food interactions with Izervay. If you’d like to learn more about eating certain foods during treatment with Izervay, talk with your doctor.

Izervay and vaccines

There aren’t any known interactions between Izervay and vaccines. Talk with your doctor or pharmacist to see whether you’re due for any vaccines.

Izervay and lab tests

Izervay isn’t known to interact with any lab tests. If you have concerns about this medication interacting with lab tests, talk with your doctor.

IZERVAY INTERACTION WITH CANNABIS OR CBD

Cannabis (often called marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Izervay. However, as with any drug or supplement, talk with your doctor before using cannabis in combination with Izervay. The impact of cannabis may affect how well you stick to your Izervay treatment plan.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Certain medical conditions and other factors may increase the risk of interactions with Izervay. Before you take this drug, be sure to talk with your doctor about your health history. Izervay may not be the right treatment option if you have certain medical conditions or other factors affecting your health.

Health conditions or factors that might interact with Izervay include:

  • Eye infection or inflammation: If you have an infection or inflammation in your eye, your doctor will likely not administer Izervay. For more information, see the “When to avoid Izervay” section above.
  • Glaucoma: Receiving an injection of Izervay in your eye can temporarily increase the pressure in your eye. If you have glaucoma or raised pressure in your eye, talk with your doctor about whether treatment with Izervay is right for you.
  • Allergic reaction: If you’ve had an allergic reaction to Izervay or any of its ingredients, your doctor will likely not prescribe Izervay. Using the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.
  • Breastfeeding: It’s not known whether it’s safe to receive Izervay while breastfeeding. There isn’t enough information to determine whether the drug passes into breast milk or what effects Izervay may have on a child who’s breastfed. If you’re breastfeeding or planning to, talk with your doctor before using Izervay. They can talk with you about treatment options and ways to feed your child.
  • Pregnancy: There haven’t been enough clinical trials to determine whether Izervay is safe to receive while pregnant. Animal studies did not find any harmful effects when the drug was given to pregnant females. However, it’s important to note that animal studies don’t always indicate what may happen in humans. If you’re pregnant or planning to become pregnant, tell your doctor before starting Izervay. They can advise you on the right treatment plan for you.

You can take certain steps to help prevent interactions with Izervay. Your doctor and pharmacist are key resources, so reach out to them before starting treatment. For example, you should plan to do the following:

  • Let them know if you drink alcohol or use cannabis.
  • Tell them about any other medications you take, as well as any supplements, herbs, and vitamins.
  • Create a medication list, which your doctor and pharmacist can help you fill out.

It’s also important to read the Izervay label and other paperwork that may come with the drug. The label may have colored stickers that mention an interaction. And the paperwork, sometimes called the medication guide or patient package insert, may contain details about interactions.

If Izervay doesn’t come with paperwork, you can ask your pharmacist to print a copy. If you need help reading or understanding this information, ask your doctor or pharmacist.

Besides learning about interactions, you may want to find out more about Izervay. These resources might help:

  • Overview of Izervay: For a general overview of Izervay, you can see this article.
  • Facts about your condition: To learn more about your condition, see our eye health hub.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.