Elahere (mirvetuximab soravtansine-gynx) is a brand-name drug prescribed for certain types of ovarian cancer in adults. Elahere comes as an intravenous (IV) infusion that’s given by a healthcare professional, typically once every 21 days.

Elahere is approved by the Food and Drug Administration (FDA) to treat certain types of ovarian cancer, including cancer of the fallopian tubes and peritoneum, in adults. In this article, the term “ovarian cancer” describes cancer of the ovaries, fallopian tubes, or peritoneum.

Elahere is a biologic and belongs to a drug class called antibody-drug conjugates. Elahere is not available in a biosimilar version. (The active ingredient is mirvetuximab soravtansine-gynx. The reason “-gynx” appears at the end of the drug’s name is to show that it’s distinct from similar medications that may be created in the future.)

Keep reading for specific information about the dosage of Elahere, including its strength and how to take the medication. For a comprehensive look at Elahere, see this article.

Note: This article describes the typical dosage of Elahere provided by the drug’s manufacturer. However, your doctor will prescribe the Elahere dosage that’s right for you.

Read below for the recommended dosage of Elahere and other details about the drug.

Elahere form

Elahere comes as a solution that’s given as an IV infusion by a healthcare professional.

Elahere strength

Elahere comes in one strength of 100 milligrams per 20 milliliters (mg/mL) of solution (5 mg/mL).

Typical dosages

The following information describes the dosage that’s commonly prescribed or recommended. However, your doctor will determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those shown below.

Dosage for ovarian cancer

Doctors may prescribe Elahere to treat certain forms of ovarian cancer. Elahere is typically taken with other drugs. Elahere dosing is based on your adjusted ideal body weight (AIBW) in kilograms (kg). Your doctor will calculate your AIBW using your weight, height, and other factors. For reference, 1 kg is about 2.2 pounds (lb).

The recommended dose of Elahere for ovarian cancer is 6 milligrams per kilogram (mg/kg) of AIBW. You’ll receive this dose once every 3 weeks (21 days).

For more information about your specific dosage, talk with your doctor.

How Elahere is given

Your doctor or another healthcare professional will give you the IV infusion of Elahere. You’ll likely go to your doctor’s office, an infusion center, or a hospital to receive your infusion. The infusion takes 1 to 3 hours.

Your doctor will prescribe other drugs right before your Elahere infusion. These medications help reduce the risk of infusion-related side effects such as nausea and vomiting. Examples include:

  • a corticosteroid such as dexamethasone (Decadron)
  • an antihistamine such as diphenhydramine (Benadryl)
  • fever-reducing medication such as acetaminophen (Tylenol)
  • medication to help prevent nausea and vomiting, such as ondansetron (Zofran)

To learn more about starting Elahere, talk with your doctor. You can also read about what to expect on the drug manufacturer’s website.

Long-term treatment

Elahere is meant to be a long-term treatment. If you and your doctor determine that Elahere is safe and effective for you, you’ll likely receive the drug long term.

Before you start taking Elahere, your doctor will discuss your treatment plan with you.

Below are some common questions about Elahere and dosage.

What should I do for a missed dose of Elahere?

If you miss your appointment for an Elahere infusion, call your doctor’s office as soon as possible to reschedule. They’ll adjust your dosing schedule as needed.

If you need help remembering your appointments, try setting an alarm or downloading a reminder app on your phone.

How long does it take for Elahere to start working?

Elahere starts to work after your first dose. Because of how the drug works, you likely won’t feel the drug working in your body. But your doctor will monitor you during treatment to check whether the drug is working to treat your condition.

Talk with your doctor if you have questions about what to expect with Elahere treatment. If you’d like more information about your condition, you can refer to this list of ovarian cancer articles.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.